Pathophysiological study of iron-deficiency anemia in adolescence.

pable splenomegaly. Vitamin E is well known to have a close relationship with the endocrine system. For instance, the reduced function of the endocrine organs, mainly sex glands, has been reported in vitamin E deficient rats (Evans 1922, Bisceglie 1928, Martin 1939). On the other hands, close relationship between vitamin E and anemia has also been reported by several investigators such as Dinning (1957)1 and Porter (1966) who noted remarkable anemia in vitamin E deficient monkeys under observation. Adolescence is a period when the function of the endocrine system becomes